node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2mit | CG34308 | FBpp0303176 | FBpp0401591 | 2mit, isoform B; 2mit (2mit) encodes a putative leucine-rich repeat transmembrane protein that is mainly expressed in the developing central nervous system. In the adult, it has a role in short-term memory. | RING-type domain-containing protein; Ubiquitin-like protein conjugating enzyme binding; ubiquitin protein ligase activity; metal ion binding. It is involved in the biological process described with: ER-associated misfolded protein catabolic process; ubiquitin-dependent protein catabolic process. | 0.835 |
2mit | elm | FBpp0303176 | FBpp0306969 | 2mit, isoform B; 2mit (2mit) encodes a putative leucine-rich repeat transmembrane protein that is mainly expressed in the developing central nervous system. In the adult, it has a role in short-term memory. | Ethanol sensitive with low memory, isoform A; Calcium ion binding. | 0.403 |
CG10505 | CG31793 | FBpp0071545 | FBpp0080682 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | 0.431 |
CG10505 | CG34308 | FBpp0071545 | FBpp0401591 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | RING-type domain-containing protein; Ubiquitin-like protein conjugating enzyme binding; ubiquitin protein ligase activity; metal ion binding. It is involved in the biological process described with: ER-associated misfolded protein catabolic process; ubiquitin-dependent protein catabolic process. | 0.539 |
CG10505 | CG6766 | FBpp0071545 | FBpp0079892 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | FI04402p; It is involved in the biological process described with: retrograde protein transport, ER to cytosol; ubiquitin-dependent ERAD pathway. | 0.499 |
CG10505 | Der-1 | FBpp0071545 | FBpp0306799 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | Derlin-1; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. May also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation. | 0.534 |
CG10505 | Der-2 | FBpp0071545 | FBpp0082758 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. | 0.530 |
CG10505 | Hrd3 | FBpp0071545 | FBpp0302807 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | HMG-coA reductase degradation 3, isoform A; It is involved in the biological process described with: ubiquitin-dependent ERAD pathway. | 0.499 |
CG10505 | RpL40 | FBpp0071545 | FBpp0306837 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.416 |
CG10505 | RpS27A | FBpp0071545 | FBpp0079606 | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involve [...] | 0.416 |
CG31793 | CG10505 | FBpp0080682 | FBpp0071545 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | 0.431 |
CG31793 | CG34308 | FBpp0080682 | FBpp0401591 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | RING-type domain-containing protein; Ubiquitin-like protein conjugating enzyme binding; ubiquitin protein ligase activity; metal ion binding. It is involved in the biological process described with: ER-associated misfolded protein catabolic process; ubiquitin-dependent protein catabolic process. | 0.539 |
CG31793 | CG6766 | FBpp0080682 | FBpp0079892 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | FI04402p; It is involved in the biological process described with: retrograde protein transport, ER to cytosol; ubiquitin-dependent ERAD pathway. | 0.501 |
CG31793 | Der-1 | FBpp0080682 | FBpp0306799 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | Derlin-1; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. May also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation. | 0.534 |
CG31793 | Der-2 | FBpp0080682 | FBpp0082758 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. | 0.530 |
CG31793 | Hrd3 | FBpp0080682 | FBpp0302807 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | HMG-coA reductase degradation 3, isoform A; It is involved in the biological process described with: ubiquitin-dependent ERAD pathway. | 0.499 |
CG31793 | RpL40 | FBpp0080682 | FBpp0306837 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...] | 0.404 |
CG31793 | RpS27A | FBpp0080682 | FBpp0079606 | LD28489p; ATPase activity; ATPase-coupled transmembrane transporter activity; ATP binding. It is involved in the biological process described with: transmembrane transport. | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involve [...] | 0.416 |
CG34308 | 2mit | FBpp0401591 | FBpp0303176 | RING-type domain-containing protein; Ubiquitin-like protein conjugating enzyme binding; ubiquitin protein ligase activity; metal ion binding. It is involved in the biological process described with: ER-associated misfolded protein catabolic process; ubiquitin-dependent protein catabolic process. | 2mit, isoform B; 2mit (2mit) encodes a putative leucine-rich repeat transmembrane protein that is mainly expressed in the developing central nervous system. In the adult, it has a role in short-term memory. | 0.835 |
CG34308 | CG10505 | FBpp0401591 | FBpp0071545 | RING-type domain-containing protein; Ubiquitin-like protein conjugating enzyme binding; ubiquitin protein ligase activity; metal ion binding. It is involved in the biological process described with: ER-associated misfolded protein catabolic process; ubiquitin-dependent protein catabolic process. | Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1. | 0.539 |