STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG5267Uncharacterized protein; It is involved in the biological process described with: multicellular organism reproduction. (201 aa)    
Predicted Functional Partners:
Sfp84E
Seminal fluid protein 84E; It is involved in the biological process described with: multicellular organism reproduction.
      
 0.839
Sfp79B
Seminal fluid protein 79B; It is involved in the biological process described with: multicellular organism reproduction.
      
 0.834
aqrs
Aquarius (aqrs) encodes a predicted serine protease produced by the male accessory glands and transferred to females during mating. It is required for the binding of the product of SP to sperm and for the transfer of the products of lectin-46Ca and lectin-46Cb to females during mating.
   
  
 0.744
intr
Intrepid; Serine-type endopeptidase activity. It is involved in the biological process described with: sperm storage; proteolysis; negative regulation of female receptivity, post-mating; multicellular organism reproduction.
   
  
 0.682
antr
Antares, isoform B; It is involved in the biological process described with: negative regulation of female receptivity, post-mating; sperm storage; multicellular organism reproduction.
   
  
 0.664
CG9997
Uncharacterized protein, isoform A; CG9997 encodes a protein with homology to serine-type endopeptidases, but is not predicted to have catalytic activity due to mutations in its active site. It is produced in the male accessory gland and transferred to females during mating. In males, it is required for other seminal proteins to be transferred to mated females. In mated females, it is required for the binding of the product of SP to sperm and for the maintenance of long-term post-mating responses.
   
  
 0.635
Sems
Seminase (Sems) encodes a serine protease produced in male's accessory glands and transferred to females during mating. It is an essential component in the pathway for proteolytic processing of different seminal proteins. It cleaves the metalloprotease encoded by Semp1, which in turn also cleaves the seminal proteins encoded by Acp26Aa and Acp36DE. It is also required for sperm release from storage via regulation of the product of SP.
   
  
 0.627
BG642163
Male accessory gland protein; It is involved in the biological process described with: multicellular organism reproduction.
   
  
 0.614
CG43145
Uncharacterized protein; Serine-type endopeptidase inhibitor activity.
      
 0.602
CG17575
Uncharacterized protein, isoform B; CG17575 encodes a cysteine-rich secretory protein produced in the male accessory glands and transferred to females during mating. In mated females, it is required for the binding of the product of SP to sperm and for the consequent maintenance of long-term post-mating responses.
      
 0.601
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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