STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jon74EJonah 74E; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. (271 aa)    
Predicted Functional Partners:
epsilonTry
Trypsin epsilon; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.896
alphaTry
Trypsin alpha; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis.
  
  
0.882
betaTry
betaTrypsin (betaTry) encodes a putative digestive enzyme with predicted serine-type endopeptidase activity. betaTry is highly expressed and enriched in the midgut, an organ involved in digestion; Belongs to the peptidase S1 family.
  
  
0.873
CG31233
Metalloaminopeptidase activity; zinc ion binding; peptide binding. It is involved in the biological process described with: peptide catabolic process; proteolysis.
   
  
 0.832
Jon25Biii
Jonah 25Biii; Serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.826
CG17633
Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis; Belongs to the peptidase M14 family.
   
 
 0.823
Jon25Bii
Jonah 25Bii, isoform A; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.823
CG11911
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.797
Jon65Aiv
Jonah 65Aiv; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.793
CG31343
Aminopeptidase; Zinc ion binding; peptide binding; metalloaminopeptidase activity. It is involved in the biological process described with: peptide catabolic process; proteolysis.
   
  
 0.788
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.