STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Teh4TipE-like protein 4; Sodium channel regulator activity. It is involved in the biological process described with: regulation of sodium ion transport. (524 aa)    
Predicted Functional Partners:
Teh2
TipE homolog 2, isoform B; tipE homolog 2 (Teh2) encodes a protein involved in regulation of sodium transport.
 
 
  
 0.947
tipE
Protein tipE; Enhances para sodium channel function. Required during pupal development to rescue adult paralysis and also protects adult flies against heat-induced lethality.
 
 
  
 0.926
Teh1
TipE homolog 1, isoform B; tipE homolog 1 (Teh1) encodes a protein involved in regulation of sodium transport.
 
 
  
 0.922
CG18675
Cilia- and flagella-associated protein 298; It is involved in the biological process described with: regulation of cilium movement; Belongs to the CFAP298 family.
   
  
 0.703
VhaM9.7-c
V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
   
  
 0.684
cmpy
Crimpy, isoform C; BMP binding; insulin-like growth factor binding.
   
    0.672
para
Sodium channel protein para; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Belongs to the sodium channel (TC 1.A.1.10) family. Para subfamily.
   
  
 0.628
CG42540
Band 7 protein CG42540.
   
    0.611
dpr20
Defective proboscis extension response 20; It is involved in the biological process described with: synapse organization; sensory perception of chemical stimulus.
   
    0.601
CG31760
Probable G-protein coupled receptor CG31760; G protein-coupled receptor activity. It is involved in the biological process described with: G protein-coupled receptor signaling pathway.
   
    0.567
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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