Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AWZ03_014349Uncharacterized protein. (612 aa)    
Predicted Functional Partners:
AWZ03_005793
Ubiquitin-like domain-containing protein.
    
 0.971
AWZ03_008634
Homeobox domain-containing protein.
   
   0.924
AWZ03_003904
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 0.880
AWZ03_011491
VWFA domain-containing protein.
   
 
 0.860
AWZ03_009826
TPR_REGION domain-containing protein.
    
 
 0.791
AWZ03_007919
BTB domain-containing protein.
    
   0.767
AWZ03_011823
PCI domain-containing protein.
    
 0.765
AWZ03_011032
MPN domain-containing protein.
    
 0.753
AWZ03_009705
PCI domain-containing protein.
    
 0.732
AWZ03_010689
Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.
    
  0.725
Your Current Organism:
Drosophila navojoa
NCBI taxonomy Id: 7232
Other names: D. navojoa
Server load: medium (46%) [HD]