AWZ03_013255 protein (Drosophila navojoa) - STRING interaction network

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Score

AWZ03_013255

Uncharacterized protein. (213 aa)

Predicted Functional Partners:

AWZ03_000286

0.912

AWZ03_008839

0.852

AWZ03_010400

0.848

AWZ03_006310

0.841

AWZ03_007778

0.792

AWZ03_007527

0.754

AWZ03_007269

0.752

AWZ03_002570

0.748

AWZ03_012648

0.689

AWZ03_004946

0.669

Your Current Organism:

Drosophila navojoa

NCBI taxonomy Id: 7232
Other names: D. navojoa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AWZ03_000286	AWZ03_004946	A0A484C3C5	A0A484BIM4	FYVE-type domain-containing protein.	Uncharacterized protein.	0.747
AWZ03_000286	AWZ03_007269	A0A484C3C5	A0A484BC55	FYVE-type domain-containing protein.	Uncharacterized protein.	0.609
AWZ03_000286	AWZ03_007527	A0A484C3C5	A0A484BBH7	FYVE-type domain-containing protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.893
AWZ03_000286	AWZ03_008839	A0A484C3C5	A0A484B7N0	FYVE-type domain-containing protein.	Uncharacterized protein.	0.689
AWZ03_000286	AWZ03_013255	A0A484C3C5	A0A484AV37	FYVE-type domain-containing protein.	Uncharacterized protein.	0.912
AWZ03_002570	AWZ03_007778	A0A484BSS9	A0A484BAJ8	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.693
AWZ03_002570	AWZ03_013255	A0A484BSS9	A0A484AV37	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Uncharacterized protein.	0.748
AWZ03_004946	AWZ03_000286	A0A484BIM4	A0A484C3C5	Uncharacterized protein.	FYVE-type domain-containing protein.	0.747
AWZ03_004946	AWZ03_007527	A0A484BIM4	A0A484BBH7	Uncharacterized protein.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.999
AWZ03_004946	AWZ03_013255	A0A484BIM4	A0A484AV37	Uncharacterized protein.	Uncharacterized protein.	0.669
AWZ03_006310	AWZ03_013255	A0A484BEP7	A0A484AV37	Rab-GAP TBC domain-containing protein.	Uncharacterized protein.	0.841
AWZ03_007269	AWZ03_000286	A0A484BC55	A0A484C3C5	Uncharacterized protein.	FYVE-type domain-containing protein.	0.609
AWZ03_007269	AWZ03_013255	A0A484BC55	A0A484AV37	Uncharacterized protein.	Uncharacterized protein.	0.752
AWZ03_007527	AWZ03_000286	A0A484BBH7	A0A484C3C5	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	FYVE-type domain-containing protein.	0.893
AWZ03_007527	AWZ03_004946	A0A484BBH7	A0A484BIM4	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Uncharacterized protein.	0.999
AWZ03_007527	AWZ03_013255	A0A484BBH7	A0A484AV37	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Uncharacterized protein.	0.754
AWZ03_007778	AWZ03_002570	A0A484BAJ8	A0A484BSS9	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.693
AWZ03_007778	AWZ03_013255	A0A484BAJ8	A0A484AV37	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Uncharacterized protein.	0.792
AWZ03_008839	AWZ03_000286	A0A484B7N0	A0A484C3C5	Uncharacterized protein.	FYVE-type domain-containing protein.	0.689
AWZ03_008839	AWZ03_013255	A0A484B7N0	A0A484AV37	Uncharacterized protein.	Uncharacterized protein.	0.852