Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AWZ03_012930Uncharacterized protein. (379 aa)    
Predicted Functional Partners:
AWZ03_012345
J domain-containing protein.
   
   0.954
AWZ03_000345
Uncharacterized protein.
    
 
 0.840
Fen1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 
 0.776
AWZ03_005721
Uncharacterized protein.
   
 
 0.718
AWZ03_013361
RING-type domain-containing protein.
    
 
 0.698
AWZ03_006234
Uncharacterized protein.
   
   0.688
AWZ03_010851
Uncharacterized protein.
    
 
 0.682
AWZ03_007648
SF4 helicase domain-containing protein.
    
 
 0.641
AWZ03_011708
Uncharacterized protein.
    
   0.638
AWZ03_009391
Ku_PK_bind domain-containing protein.
    
 
 0.615
Your Current Organism:
Drosophila navojoa
NCBI taxonomy Id: 7232
Other names: D. navojoa
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