Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AWZ03_012987E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (751 aa)    
Predicted Functional Partners:
AWZ03_012984
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
 
     0.922
AWZ03_014364
Uncharacterized protein.
   
  
 0.654
AWZ03_004847
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
    0.569
AWZ03_003297
RING-type domain-containing protein.
   
 
 0.542
AWZ03_006921
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.495
AWZ03_001850
Peptidase S1 domain-containing protein.
      
 0.460
AWZ03_007745
Uncharacterized protein.
      
 0.444
Your Current Organism:
Drosophila navojoa
NCBI taxonomy Id: 7232
Other names: D. navojoa
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