STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AWZ03_009460B30.2/SPRY domain-containing protein. (573 aa)    
Predicted Functional Partners:
AWZ03_001038
WD_REPEATS_REGION domain-containing protein.
    
 0.999
AWZ03_007367
Uncharacterized protein.
    
 0.996
AWZ03_012571
Uncharacterized protein.
   
 0.994
AWZ03_011573
Uncharacterized protein.
    
 0.979
AWZ03_010204
Histone-lysine N-methyltransferase trithorax; Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes. Acts as an activator of BX-C. Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo.
    
 0.968
AWZ03_005029
Uncharacterized protein.
    
 0.956
AWZ03_004970
Uncharacterized protein.
    
 0.956
AWZ03_006133
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.945
AWZ03_009688
WD_REPEATS_REGION domain-containing protein.
   
 0.921
AWZ03_000316
WD_REPEATS_REGION domain-containing protein.
   
 0.921
Your Current Organism:
Drosophila navojoa
NCBI taxonomy Id: 7232
Other names: D. navojoa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.