YFH1 protein (Trachipleistophora hominis) - STRING interaction network

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Score

YFH1

Frataxin; Promotes the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. (107 aa)

Predicted Functional Partners:

NFS1

0.999

ISU1

0.999

THOM_0371

0.879

THOM_1036

0.736

THOM_3057

0.668

THOM_2092

0.600

THOM_2079

0.550

THOM_0826

0.549

THOM_1946

0.541

THOM_0625

0.519

Your Current Organism:

Trachipleistophora hominis

NCBI taxonomy Id: 72359
Other names: T. hominis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ISU1	NFS1	B0YLW7	B0YLW6	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	0.999
ISU1	THOM_0371	B0YLW7	L7K0F4	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	Ferredoxin.	0.958
ISU1	THOM_0625	B0YLW7	L7JYK7	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	Thioredoxin/protein disulfide isomerase.	0.550
ISU1	THOM_1946	B0YLW7	L7JWI7	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	Glutaredoxin-related protein.	0.638
ISU1	THOM_2079	B0YLW7	L7JVA2	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	Molecular chaperone (DnaJ superfamily).	0.519
ISU1	THOM_3057	B0YLW7	Q8MV55	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	Molecular chaperones mortalin/PBP74/GRP75, HSP70 superfamily; Belongs to the heat shock protein 70 family.	0.856
ISU1	YFH1	B0YLW7	B0YLW8	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	Frataxin; Promotes the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways.	0.999
NFS1	ISU1	B0YLW6	B0YLW7	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	0.999
NFS1	THOM_0371	B0YLW6	L7K0F4	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	Ferredoxin.	0.988
NFS1	THOM_0625	B0YLW6	L7JYK7	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	Thioredoxin/protein disulfide isomerase.	0.870
NFS1	THOM_1036	B0YLW6	L7JY59	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	Flavohemoprotein b5+b5R; Belongs to the cytochrome b5 family.	0.487
NFS1	THOM_1946	B0YLW6	L7JWI7	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	Glutaredoxin-related protein.	0.611
NFS1	THOM_3057	B0YLW6	Q8MV55	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	Molecular chaperones mortalin/PBP74/GRP75, HSP70 superfamily; Belongs to the heat shock protein 70 family.	0.661
NFS1	YFH1	B0YLW6	B0YLW8	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	Frataxin; Promotes the assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways.	0.999
THOM_0371	ISU1	L7K0F4	B0YLW7	Ferredoxin.	Iron sulfur cluster assembly protein 1; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe- 2S] cluster is transiently assembled on the scaffold protein ISU1. In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster assembly on ISU1 depends on the function of the cysteine desul [...]	0.958
THOM_0371	NFS1	L7K0F4	B0YLW6	Ferredoxin.	Cysteine desulfurase, mitosomal; Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe- S) clusters in mitosomes.	0.988
THOM_0371	THOM_0625	L7K0F4	L7JYK7	Ferredoxin.	Thioredoxin/protein disulfide isomerase.	0.519
THOM_0371	THOM_1036	L7K0F4	L7JY59	Ferredoxin.	Flavohemoprotein b5+b5R; Belongs to the cytochrome b5 family.	0.982
THOM_0371	THOM_1946	L7K0F4	L7JWI7	Ferredoxin.	Glutaredoxin-related protein.	0.481
THOM_0371	THOM_3057	L7K0F4	Q8MV55	Ferredoxin.	Molecular chaperones mortalin/PBP74/GRP75, HSP70 superfamily; Belongs to the heat shock protein 70 family.	0.563