STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THOM_2722Histone transcription regulator HIRA, WD repeat superfamily. (1152 aa)    
Predicted Functional Partners:
THOM_2359
Histone chaperone.
    
 0.999
THOM_0773
Uncharacterized protein.
    
 0.758
THOM_0269
Nucleosome remodeling factor, subunit CAF1/NURF55/MSI1.
    
 
 0.673
THOM_2731
Histones H3 and H4.
    
 
 0.594
THOM_2474
Histones H3 and H4.
    
 
 0.594
THOM_0212
Histones H3 and H4.
    
 
 0.594
THOM_2472
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 
 0.587
THOM_0917
Putative WD40 repeat, subgroup, WD40/YVTN repeat-like-containing domain protein.
    
 
 0.487
THOM_1224
Glucose 1-dehydrogenase, 3-oxoacyl-[acyl-carrier-protein] reductase.
    
 0.440
THOM_1225
Putative short-chain dehydrogenase/reductase SDR.
    
 0.440
Your Current Organism:
Trachipleistophora hominis
NCBI taxonomy Id: 72359
Other names: T. hominis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.