node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | THOM_0067 | L7JSI1 | L7JZN4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative MutL, dimerization, DNA mismatch repair protein. | 0.730 |
FEN1 | THOM_0558 | L7JSI1 | L7JYE2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Mismatch repair ATPase MSH6 (MutS family). | 0.894 |
FEN1 | THOM_1404 | L7JSI1 | L7JVX5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein-MLH1 family. | 0.748 |
FEN1 | THOM_1405 | L7JSI1 | L7JW26 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein-MLH1 family. | 0.748 |
FEN1 | THOM_2122 | L7JSI1 | L7JTW9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.997 |
FEN1 | THOM_2437 | L7JSI1 | L7JUF0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA mismatch repair protein-MLH2/PMS1/Pms2 family. | 0.781 |
FEN1 | THOM_2653 | L7JSI1 | L7JSY7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Mismatch repair ATPase MSH2 (MutS family). | 0.809 |
FEN1 | THOM_2655 | L7JSI1 | L7JTP0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Putative DNA mismatch repair protein MutS, core protein. | 0.809 |
FEN1 | THOM_2808 | L7JSI1 | L7JS75 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 5'-3' exonuclease. | 0.821 |
THOM_0067 | FEN1 | L7JZN4 | L7JSI1 | Putative MutL, dimerization, DNA mismatch repair protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.730 |
THOM_0067 | THOM_0558 | L7JZN4 | L7JYE2 | Putative MutL, dimerization, DNA mismatch repair protein. | Mismatch repair ATPase MSH6 (MutS family). | 0.912 |
THOM_0067 | THOM_1404 | L7JZN4 | L7JVX5 | Putative MutL, dimerization, DNA mismatch repair protein. | DNA mismatch repair protein-MLH1 family. | 0.941 |
THOM_0067 | THOM_1405 | L7JZN4 | L7JW26 | Putative MutL, dimerization, DNA mismatch repair protein. | DNA mismatch repair protein-MLH1 family. | 0.941 |
THOM_0067 | THOM_2122 | L7JZN4 | L7JTW9 | Putative MutL, dimerization, DNA mismatch repair protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.790 |
THOM_0067 | THOM_2653 | L7JZN4 | L7JSY7 | Putative MutL, dimerization, DNA mismatch repair protein. | Mismatch repair ATPase MSH2 (MutS family). | 0.859 |
THOM_0067 | THOM_2655 | L7JZN4 | L7JTP0 | Putative MutL, dimerization, DNA mismatch repair protein. | Putative DNA mismatch repair protein MutS, core protein. | 0.859 |
THOM_0067 | THOM_2808 | L7JZN4 | L7JS75 | Putative MutL, dimerization, DNA mismatch repair protein. | 5'-3' exonuclease. | 0.858 |
THOM_0558 | FEN1 | L7JYE2 | L7JSI1 | Mismatch repair ATPase MSH6 (MutS family). | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.894 |
THOM_0558 | THOM_0067 | L7JYE2 | L7JZN4 | Mismatch repair ATPase MSH6 (MutS family). | Putative MutL, dimerization, DNA mismatch repair protein. | 0.912 |
THOM_0558 | THOM_1404 | L7JYE2 | L7JVX5 | Mismatch repair ATPase MSH6 (MutS family). | DNA mismatch repair protein-MLH1 family. | 0.921 |