STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THOM_2653Mismatch repair ATPase MSH2 (MutS family). (201 aa)    
Predicted Functional Partners:
THOM_0558
Mismatch repair ATPase MSH6 (MutS family).
  
0.959
THOM_2437
DNA mismatch repair protein-MLH2/PMS1/Pms2 family.
  
 0.920
THOM_2808
5'-3' exonuclease.
   
 0.909
THOM_2122
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.883
THOM_1404
DNA mismatch repair protein-MLH1 family.
  
 0.877
THOM_1405
DNA mismatch repair protein-MLH1 family.
  
 0.877
THOM_0067
Putative MutL, dimerization, DNA mismatch repair protein.
  
 0.859
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.809
THOM_2152
Putative starch-binding protein.
   
 
 0.772
THOM_2655
Putative DNA mismatch repair protein MutS, core protein.
 
      0.766
Your Current Organism:
Trachipleistophora hominis
NCBI taxonomy Id: 72359
Other names: T. hominis
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