STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THOM_1387Protein involved in cell differentiation/sexual development. (270 aa)    
Predicted Functional Partners:
THOM_1459
CCR4-NOT transcriptional regulation complex, NOT5 subunit.
    
 0.995
THOM_1289
mRNA deadenylase subunit.
   
 0.994
THOM_2909
MOT2 transcription factor.
    
 0.991
THOM_2051
Glucose-repressible alcohol dehydrogenase transcriptional effector CCR4.
    
 0.987
THOM_0807
Putative transcriptional regulator.
    
 0.987
THOM_0398
Negative regulator of transcription.
    
 0.911
THOM_0399
Negative regulator of transcription.
    
 0.911
THOM_1733
Nuclear exosomal RNA helicase MTR4, DEAD-box superfamily.
   
 
 0.888
THOM_0760
Rossmann-like alpha/beta/alpha sandwich fold containing protein.
    
 
 0.659
THOM_0817
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
    
 0.650
Your Current Organism:
Trachipleistophora hominis
NCBI taxonomy Id: 72359
Other names: T. hominis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.