STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THOM_1422Replication factor C, subunit RFC5. (325 aa)    
Predicted Functional Partners:
THOM_2324
Replication factor C, subunit RFC2.
  
0.999
THOM_1751
Replication factor C, subunit RFC3.
   
0.999
THOM_1309
Replication factor C, subunit RFC1 (Large subunit).
   
0.999
THOM_1402
Uncharacterized protein.
   
 0.999
THOM_2122
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.996
THOM_0918
Eukaryotic-type DNA primase, catalytic (Small) subunit.
   
 0.867
THOM_1356
DNA replication licensing factor, MCM5 component; Belongs to the MCM family.
   
 
 0.844
THOM_0685
Eukaryotic-type DNA primase, large subunit.
  
 0.840
THOM_2061
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
  
 0.830
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.827
Your Current Organism:
Trachipleistophora hominis
NCBI taxonomy Id: 72359
Other names: T. hominis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.