STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DsecGM216903-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (465 aa)    
Predicted Functional Partners:
DsecGM26526
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 
 0.999
DsecGM15500
GM15500; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
DsecGM11967
GM11967; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
DsecGM14397
GM14397; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.996
DsecGM17755
GM17755; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.995
DsecGM16259
GM16259.
     
 0.995
DsecGM15083
GM15083.
  
  
 0.978
DsecGM12955
GM12955.
  
 0.966
DsecGM18599
GM18599.
  
 0.965
DsecGM20345
GM20345; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.958
Your Current Organism:
Drosophila sechellia
NCBI taxonomy Id: 7238
Other names: D. sechellia
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