STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DsecGM17400GM17400. (169 aa)    
Predicted Functional Partners:
DsecGM23127
GM23127.
   
 0.664
DsecGM24071
GM24071.
    
 0.661
DsecGM26032
GM26032; Belongs to the peptidase S1 family.
    
 0.652
DsecGM24947
GM24947; Belongs to the heat shock protein 70 family.
    
 
 0.648
GM20779
ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]
    
 
 0.644
DsecGM26147
GM26147.
      
 0.618
DsecGM24815
Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.
    
 
 0.615
DsecGM15583
GM15583.
   
  
 0.613
DsecGM12261
GM12261.
      
 0.511
DsecGM18129
GM18129.
  
 
  0.511
Your Current Organism:
Drosophila sechellia
NCBI taxonomy Id: 7238
Other names: D. sechellia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.