STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DsecGM22481GM22481. (1050 aa)    
Predicted Functional Partners:
DsecGM23618
GM23618.
   
 0.900
DsecGM15394
GM15394.
   
 0.872
DsecGM16752
GM16752.
   
 0.870
DsecGM17932
GM17932.
    
 0.858
DsecGM18174
GM18174.
   
 0.849
DsecGM24628
GM24628.
    
 0.843
spn-E
Probable ATP-dependent RNA helicase spindle-E; Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons. Involved in the repression of LTR retrotransposon copia. Also involved in telomere regulation by repres [...]
   
 0.839
DsecGM26290
Splicing factor 3B subunit 5; Belongs to the SF3B5 family.
    
 0.837
DsecGM14250
GM14250.
    
 0.831
DsecGM14575
GM14575.
    
 0.826
Your Current Organism:
Drosophila sechellia
NCBI taxonomy Id: 7238
Other names: D. sechellia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.