STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DsecGM25965GM25965. (880 aa)    
Predicted Functional Partners:
DsecGM15842
Receptor protein-tyrosine kinase.
   
 0.999
DsecGM16277
GM16277.
    
 0.648
DsecGM24397
GM24397.
      
 0.613
DsecGM21591
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; Belongs to the methyltransferase superfamily. METTL16/RlmF family.
      
 0.611
DsecGM25366
GM25366.
    
 0.547
Cirl
Latrophilin Cirl.
    
   0.534
DsecGM25007
GM25007.
   
  
 0.529
DsecGM12935
GM12935.
    
 0.513
DsecGM11803
GM11803.
      
 0.504
otk
Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons (By similarity).
    
 0.501
Your Current Organism:
Drosophila sechellia
NCBI taxonomy Id: 7238
Other names: D. sechellia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.