STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DsecGM10652GM10652. (338 aa)    
Predicted Functional Partners:
DsecGM10663
GM10663.
 
      0.849
DsecGM19264
GM19264.
    
 0.817
DsecGM26636
GM26636.
    
 
 0.726
DsecGM21859
GM21859.
    
 
 0.714
DsecGM22291
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
   
 
 0.713
DsecGM17716
GM17716; Belongs to the peptidase S8 family.
     
 0.713
DsecGM10127
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
 0.704
DsecGM13432
GM13432.
     
 0.628
DsecGM13433
GM13433.
     
 0.628
DsecGM26178
GM26178.
    
 0.615
Your Current Organism:
Drosophila sechellia
NCBI taxonomy Id: 7238
Other names: D. sechellia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.