STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DsimGD24041Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2537 aa)    
Predicted Functional Partners:
DsimGD20123
GD20123.
   
 0.992
DsimGD22184
GD22184.
   
 0.986
DsimGD21946
GD21946.
   
 0.820
DsimGD10984
GD10984.
   
 0.807
DsimGD13444
GD13444.
    
 0.712
DsimGD12991
GD12991.
   
 0.697
DsimGD22951
GD22951.
    
 0.681
DsimGD21164
GD21164.
      
 0.670
DsimGD21120
GD21120.
   
 
 0.616
DsimGD21121
GD21121.
   
 
 0.616
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.