STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DsimGD20169GD20169. (487 aa)    
Predicted Functional Partners:
DsimGD18329
GD18329.
    
 
 0.860
DsimGD22951
GD22951.
    
 0.732
Dsim_GD25924
WD repeat-containing protein 48 homolog; Regulator of deubiquitinating complexes. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate (By similarity).
  
 
0.687
DsimGD15475
GD15475.
   
 0.674
Dsimbip2
Bip2.
   
 0.674
DsimGD20610
GD20610.
      
 0.657
DsimGD17368
GD17368.
    
 0.626
DsimGD21960
GD21960.
    
 0.619
DsimGD14027
GD14027.
     
 0.613
DsimGD12884
GD12884.
   
 0.613
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.