STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DsimGD15659Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (607 aa)    
Predicted Functional Partners:
DsimGD25481
GD25481; Belongs to the actin family.
    
 0.997
DsimGD19207
GD19207; Belongs to the actin family.
   
 0.997
DsimGD24565
GD24565.
    
 0.995
DsimGD18681
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
    
 0.995
DsimGD20113
GD20113.
    
 0.982
DsimGD13805
GD13805.
    
 0.961
DsimGD14791
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
   
 0.961
DsimGD10370
GD10370.
    
 0.957
DsimGD14764
GD14764.
    
 0.957
DsimGD10763
GD10763.
    
 0.947
Your Current Organism:
Drosophila simulans
NCBI taxonomy Id: 7240
Other names: D. simulans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.