STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvirGJ12192tRNA_int_end_N2 domain-containing protein. (394 aa)    
Predicted Functional Partners:
DvirGJ22098
Sen15 domain-containing protein.
    
 0.927
DvirGJ11671
tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]
   
 0.880
DvirGJ13518
RRM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
    0.759
cbc
Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.
    
 0.751
DvirGJ22551
DALR_1 domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.686
DvirGJ12394
Uncharacterized protein.
      
 0.623
DvirGJ16733
Uncharacterized protein.
      
 0.593
DvirGJ21566
CPSF_A domain-containing protein.
     
 0.535
DvirGJ11043
Uncharacterized protein; Belongs to the universal ribosomal protein uL13 family.
      
 0.493
DvirGJ18934
DALR_1 domain-containing protein.
      
 0.445
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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