STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvirGJ10259DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (186 aa)    
Predicted Functional Partners:
DvirGJ18288
Thymidylat_synt domain-containing protein.
 
 0.999
DvirGJ14841
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.994
DvirGJ23253
Uncharacterized protein, isoform B.
  
 
 0.982
DvirGJ23941
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.979
DvirGJ13961
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
 
 0.975
DvirGJ10703
MGS domain-containing protein.
    
 0.970
DvirGJ17852
10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
  
 
 0.957
DvirGJ12582
Uncharacterized protein.
   
 
 0.956
DvirGJ22153
Thymidylate_kin domain-containing protein.
    
 0.948
DvirGJ18509
Coronin; Belongs to the WD repeat coronin family.
    
 0.940
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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