STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DvirGJ16462Uncharacterized protein. (114 aa)    
Predicted Functional Partners:
DvirGJ23294
Uncharacterized protein.
    
 0.596
DvirGJ13215
Insulin-like peptide 5.
     
 0.586
DvirGJ13218
Uncharacterized protein, isoform A.
     
 0.586
DvirGJ19327
IlGF domain-containing protein.
     
 0.585
DvirGJ12130
IlGF domain-containing protein.
     
 0.582
DvirGJ20901
RING-type domain-containing protein.
      
 0.542
DvirGJ12564
Uncharacterized protein, isoform B.
    
 
 0.490
DvirGJ13217
IlGF domain-containing protein.
     
 0.481
foxo
Forkhead box protein O; Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thord4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself m [...]
      
 0.428
DvirGJ14922
Uncharacterized protein, isoform B.
     
 0.413
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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