STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cdc37Hsp90 co-chaperone Cdc37; Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity. (399 aa)    
Predicted Functional Partners:
Hsp83
Heat shock protein 83.
   
 0.991
DvirGJ10398
HATPase_c domain-containing protein.
    
 0.948
DvirGJ24688
TPR_REGION domain-containing protein.
   
 
 0.928
DvirGJ22746
TPR_REGION domain-containing protein.
    
 
 0.928
DvirGJ20879
HATPase_c domain-containing protein.
    
 0.920
DvirGJ14201
Uncharacterized protein.
    
 0.920
DvirGJ16598
Uncharacterized protein.
    
 0.850
DvirGJ21256
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.781
ksr
Kinase suppressor of ras.
    
 0.777
DvirGJ16989
Protein kinase domain-containing protein.
    
 
 0.753
Your Current Organism:
Drosophila virilis
NCBI taxonomy Id: 7244
Other names: D. virilis
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