Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DGUA_6G000374Blast:Protein lethal(2)denticleless. (772 aa)    
Predicted Functional Partners:
DGUA_6G003007
Blast:Cullin-4B; Belongs to the cullin family.
    
 0.998
DGUA_6G015709
Blast:DNA damage-binding protein 1.
    
 0.998
DGUA_6G003679
Blast:DNA replication factor Cdt1.
   
 
 0.995
DGUA_6G000762
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.980
DGUA_6G004504
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.980
DGUA_6G018510
Blast:COP9 signalosome complex subunit 5.
    
 0.970
DGUA_6G003637
Blast:WD repeat and HMG-box DNA-binding protein 1.
   
  
 0.958
DGUA_6G008069
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
  
 0.936
DGUA_6G014657
Blast:RING-box protein 1B.
    
 0.932
DGUA_6G008403
Blast:RING-box protein 1A.
    
 0.932
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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