STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G000209Blast:Spatacsin. (1816 aa)    
Predicted Functional Partners:
DGUA_6G012451
Blast:Zinc finger FYVE domain-containing protein 26 homolog.
   
 
 0.794
DGUA_6G019795
Blast:Cyclin-G-associated kinase.
      
 0.680
DGUA_6G018497
Blast:Protein spartin.
      
 0.623
DGUA_6G020337
Blast:Paraplegin.
      
 0.620
DGUA_6G003178
Blast:Synaptojanin-1.
      
 0.549
DGUA_6G002834
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
      
 0.542
DGUA_6G005975
Blast:Ataxin-2 homolog.
      
 0.538
DGUA_6G015274
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
      
 0.537
DGUA_6G019290
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
      
 0.537
DGUA_6G005144
Blast:Serine protease HTRA2, mitochondrial.
   
  
 0.536
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.