Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G001172Blast:Microtubule-associated protein RP/EB family member 1. (262 aa)    
Predicted Functional Partners:
DGUA_6G016135
Blast:Cytoskeleton-associated protein 5.
   
 0.930
DGUA_6G008187
Blast:Mitotic spindle assembly checkpoint protein MAD2A.
   
 0.906
DGUA_6G017650
Blast:Mitotic checkpoint protein BUB3.
   
 0.900
Lis-1
Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes.
   
 0.899
DGUA_6G011694
Blast:Restin homolog.
    
 0.890
DGUA_6G011142
Blast:Cytoplasmic dynein 1 intermediate chain.
   
 0.875
DGUA_6G000351
Blast:Mitotic spindle assembly checkpoint protein MAD1.
    
 0.868
DGUA_6G006031
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.863
DGUA_6G002967
Blast:Probable dynactin subunit 2.
    
 0.840
DGUA_6G012354
Blast:Centromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 0.827
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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