Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G001605Blast:Cyclin-dependent kinase inhibitor 1. (244 aa)    
Predicted Functional Partners:
DGUA_6G014300
Blast:G1/S-specific cyclin-E; Belongs to the cyclin family.
   
 0.999
DGUA_6G008616
Blast:G1/S-specific cyclin-D2; Belongs to the cyclin family.
   
 0.996
DGUA_6G019750
Blast:S-phase kinase-associated protein 2.
    
 0.996
DGUA_6G007313
Blast:NADH-cytochrome b5 reductase 3; Belongs to the cyclin family.
   
 0.994
DGUA_6G017895
Blast:Cell division control protein 2 cognate; Belongs to the protein kinase superfamily.
   
 0.994
DGUA_6G016123
Non-specific serine/threonine protein kinase.
    
 0.988
DGUA_6G002110
Blast:Dolichol kinase; Belongs to the protein kinase superfamily.
   
 0.986
DGUA_6G019383
Blast:Retinoblastoma family protein.
    
 0.978
DGUA_6G004883
Blast:Exportin-1.
    
 0.973
DGUA_6G017809
Blast:Cellular tumor antigen p53.
    
 0.962
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (46%) [HD]