Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G001522Blast:GTP-binding protein Rit2. (261 aa)    
Predicted Functional Partners:
DGUA_6G011346
Blast:Raf homolog serine/threonine-protein kinase phl.
    
 0.936
DGUA_6G015583
Blast:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.
   
 0.882
DGUA_6G006996
Blast:Ral guanine nucleotide dissociation stimulator-like 1.
    
 0.831
DGUA_6G015585
Blast:Glutamate receptor ionotropic, kainate 2.
   
 0.825
DGUA_6G016332
Blast:RalA-binding protein 1.
    
 0.816
DGUA_6G014432
Blast:Protein son of sevenless.
    
 0.801
DGUA_6G017226
Blast:Afadin.
    
 0.782
DGUA_6G004782
Blast:Rap guanine nucleotide exchange factor 2.
    
 0.781
DGUA_6G000450
Blast:Rap guanine nucleotide exchange factor 4.
    
 0.758
DGUA_6G008594
Blast:Ras GTPase-activating protein 1.
    
 0.758
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (38%) [HD]