Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G001586Blast:Trypsin iota; Belongs to the peptidase S1 family. (252 aa)    
Predicted Functional Partners:
DGUA_6G001580
Blast:Trypsin theta; Belongs to the peptidase S1 family.
   
    0.793
DGUA_6G012560
Blast:Zinc carboxypeptidase A 1.
   
 
 0.792
DGUA_6G012559
Blast:Zinc carboxypeptidase A 1.
   
 
 0.787
DGUA_6G005279
Blast:Chymotrypsin-2; Belongs to the peptidase S1 family.
  
   
0.783
DGUA_6G008868
DUF725 domain-containing protein.
   
    0.778
DGUA_6G006154
Blast:Trypsin; Belongs to the peptidase S1 family.
  
   
0.756
DGUA_6G005363
Blast:Glutathione S-transferase D7; Belongs to the GST superfamily.
    
   0.725
DGUA_6G005301
Blast:Epididymal secretory protein E1.
   
  0.722
DGUA_6G012269
Blast:EF-hand domain-containing protein D2 homolog.
    
   0.710
DGUA_6G014983
Blast:Brachyurin; Belongs to the peptidase S1 family.
  
   
0.664
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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