Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G002518Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)    
Predicted Functional Partners:
DGUA_6G002308
Blast:Inactivation-no-after-potential D protein.
   
 0.999
DGUA_6G005868
Blast:Transient receptor potential protein; Belongs to the transient receptor (TC 1.A.4) family.
   
 0.998
DGUA_6G020082
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.992
DGUA_6G013889
Blast:Target of rapamycin; Belongs to the PI3/PI4-kinase family.
    
 0.990
DGUA_6G012578
Phosphoinositide phospholipase C.
    
 0.985
DGUA_6G002516
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
     
  0.977
DGUA_6G012200
Blast:Transient receptor potential-gamma protein; Belongs to the transient receptor (TC 1.A.4) family.
   
 0.974
DGUA_6G001612
Blast:Transient-receptor-potential-like protein; Belongs to the transient receptor (TC 1.A.4) family.
   
 0.918
DGUA_6G012382
Blast:Disks large homolog 5.
   
 0.896
DGUA_6G000796
Phospholipase.
    
 0.855
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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