Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G002421Blast:General transcription factor IIH subunit 1. (592 aa)    
Predicted Functional Partners:
DGUA_6G020285
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.999
DGUA_6G007261
Blast:DNA excision repair protein haywire.
   
 0.997
DGUA_6G002037
Blast:TFIIH basal transcription factor complex helicase XPD subunit.
   
 0.997
DGUA_6G009792
General transcription factor IIH subunit.
    
 0.997
DGUA_6G001743
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.991
DGUA_6G003797
Blast:DNA repair protein complementing XP-C cells homolog.
   
 0.991
DGUA_6G007359
Blast:General transcription factor IIE subunit 1.
   
 0.990
DGUA_6G006649
Blast:Cyclin-H; Belongs to the cyclin family.
    
 0.990
RpII215
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.980
DGUA_6G007806
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.969
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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