Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G000404Uncharacterized protein. (220 aa)    
Predicted Functional Partners:
DGUA_6G011200
Blast:Transcriptional adapter 3.
    
 0.839
DGUA_6G010206
Blast:Transcription initiation factor TFIID subunit 9.
    
 0.835
DGUA_6G015449
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
    
 0.833
DGUA_6G007942
Uncharacterized protein.
    
 0.824
DGUA_6G002388
Enhancer of polycomb-like protein.
    
 0.781
DGUA_6G001371
Blast:DNA methyltransferase 1-associated protein 1.
    
 0.778
DGUA_6G000959
Blast:SAGA-associated factor 29 homolog.
    
 0.776
DGUA_6G001448
Blast:MRG/MORF4L-binding protein.
    
 0.776
e(y)2
Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...]
    
 0.776
DGUA_6G007559
Blast:Chromatin modification-related protein MEAF6.
    
 0.775
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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