Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G002878Blast:Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1. (1993 aa)    
Predicted Functional Partners:
DGUA_6G003909
Blast:Brefeldin A-inhibited guanine nucleotide-exchange protein 2.
   
 
 0.981
DGUA_6G016062
Blast:Ras-related protein Rab-1A.
    
 0.981
DGUA_6G005415
Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.974
DGUA_6G009796
Blast:ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
    
 0.937
DGUA_6G015841
Blast:ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
    
 0.937
DGUA_6G007380
Blast:ADP-ribosylation factor-like protein 1; Belongs to the small GTPase superfamily. Arf family.
    
 0.923
DGUA_6G003523
Blast:ADP-ribosylation factor-like protein 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.879
DGUA_6G009950
Blast:ADP-ribosylation factor-like protein 5A; Belongs to the small GTPase superfamily. Arf family.
    
 0.879
DGUA_6G009827
Blast:ADP-ribosylation factor GTPase-activating protein 1.
    
 0.879
DGUA_6G020125
Blast:Cytohesin-1.
     
 0.876
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.