Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DGUA_6G002971Blast:Ryanodine receptor 44F. (5142 aa)    
Predicted Functional Partners:
DGUA_6G000031
Peptidylprolyl isomerase.
    
 0.975
DGUA_6G016005
Blast:Calmodulin-like protein 4.
    
 0.952
DGUA_6G000450
Blast:Rap guanine nucleotide exchange factor 4.
     
 0.941
DGUA_6G007782
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.940
DGUA_6G019111
Blast:Calcium/calmodulin-dependent protein kinase type II alpha chain.
    
 0.934
DGUA_6G013477
Nitric oxide synthase; Produces nitric oxide (NO).
     
 0.920
DGUA_6G011962
Serine/threonine-protein phosphatase.
    
  0.912
DGUA_6G000609
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
 
 0.912
DGUA_6G004839
Blast:Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit.
     
 0.910
DGUA_6G015992
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
     
  0.910
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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