Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G000644Blast:Probable protein BRICK1-B. (76 aa)    
Predicted Functional Partners:
DGUA_6G013448
Blast:Wiskott-Aldrich syndrome protein family member 3.
    
 0.999
DGUA_6G006860
Blast:Membrane-associated protein Hem.
    
 0.999
DGUA_6G015533
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.999
DGUA_6G015910
Blast:Abl interactor 2.
    
 0.999
DGUA_6G004755
Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.
   
 0.978
DGUA_6G013546
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.970
DGUA_6G011914
Blast:Cytoplasmic protein NCK1.
    
 0.967
DGUA_6G009528
Blast:Transcription factor 25; Belongs to the actin family.
    
 0.966
DGUA_6G009479
Blast:Protein daughter of sevenless.
    
   0.957
DGUA_6G013634
Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.
   
 0.953
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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