Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G003407Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (896 aa)    
Predicted Functional Partners:
DGUA_6G006760
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
    
 0.999
DGUA_6G006675
Autophagy-related protein 3.
    
 0.999
DGUA_6G011622
Blast:Gamma-aminobutyric acid receptor-associated protein.
   
 0.999
DGUA_6G019962
Blast:Gamma-aminobutyric acid receptor-associated protein-like 1.
   
 0.998
DGUA_6G011020
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 0.997
DGUA_6G003401
Blast:Ubiquitin-like-conjugating enzyme ATG10.
    
 0.989
DGUA_6G007947
Blast:Serine/threonine-protein kinase ULK2.
   
 
 0.957
DGUA_6G020735
Blast:Autophagy-related protein 16.
    
 0.951
DGUA_6G012822
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
   
 
 0.948
DGUA_6G009621
Blast:WD repeat domain phosphoinositide-interacting protein 2.
    
 0.946
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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