Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G003540Blast:Matrix metalloproteinase-14. (608 aa)    
Predicted Functional Partners:
DGUA_6G015463
Blast:Tissue inhibitor of metalloproteases.
   
 0.964
DGUA_6G001601
Blast:Matrix metalloproteinase-14.
    
 0.902
DGUA_6G015993
Blast:Dual specificity protein phosphatase 10.
   
  
 0.711
DGUA_6G002104
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
 0.597
DGUA_6G013701
Blast:Collagen alpha-2(IV) chain.
    
 0.593
DGUA_6G016492
Blast:Furin-like protease 1, isoforms 1/1-X/2; Belongs to the peptidase S8 family.
    
 0.592
DGUA_6G019054
Blast:Furin-like protease 2; Belongs to the peptidase S8 family.
    
 0.591
DGUA_6G006755
Blast:Collagen alpha-1(XV) chain.
   
 0.544
DGUA_6G013315
Mitogen-activated protein kinase.
      
 0.539
DGUA_6G006053
Blast:Protein lap4.
     
 0.497
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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