Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G000915Blast:Fanconi anemia group I protein homolog. (1472 aa)    
Predicted Functional Partners:
DGUA_6G005304
Blast:E3 ubiquitin-protein ligase FANCL.
    
 0.999
DGUA_6G017870
Blast:Fanconi anemia group D2 protein.
   
 0.999
DGUA_6G005246
Blast:Fanconi anemia group M protein.
   
 0.997
DGUA_6G000272
Blast:Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.
   
 0.989
DGUA_6G006341
Blast:Ubiquitin carboxyl-terminal hydrolase 1; Belongs to the peptidase C19 family.
   
 0.988
DGUA_6G007322
Blast:60S ribosomal protein L10a-2.
    
 0.983
DGUA_6G002246
Blast:WD repeat-containing protein 48 homolog.
    
 0.976
DGUA_6G012934
Blast:Ubiquitin-conjugating enzyme E2 E3.
   
 0.971
DGUA_6G013333
Blast:Ubiquitin-40S ribosomal protein S27a.
    
  0.960
DGUA_6G004852
Blast:Protein hairy.
     
  0.951
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.