Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G001066Blast:Leukocyte elastase inhibitor; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)    
Predicted Functional Partners:
DGUA_6G014098
O-acyltransferase.
   
 
 0.977
DGUA_6G018357
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
   
 
 0.849
DGUA_6G009503
Blast:Dehydrogenase/reductase SDR family member 4.
    
 0.838
DGUA_6G010435
Blast:Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.835
DGUA_6G013072
Blast:Short-chain dehydrogenase/reductase family 16C member 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.835
DGUA_6G013941
Blast:Short-chain dehydrogenase/reductase family 16C member 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.835
DGUA_6G012090
Blast:Probable ATP-dependent RNA helicase DHX35; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.835
DGUA_6G005180
Blast:Carotenoid isomerooxygenase.
     
 0.568
DGUA_6G003161
Receptor protein-tyrosine kinase.
    
 0.525
DGUA_6G020184
Alcohol dehydrogenase.
     
  0.504
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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