DGUA_6G006507 protein (Drosophila guanche) - STRING interaction network

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Score

DGUA_6G006507

Blast:Tudor domain-containing protein 3. (835 aa)

Predicted Functional Partners:

DGUA_6G008900

0.997

DGUA_6G003919

0.989

DGUA_6G019357

0.979

DGUA_6G005916

0.975

DGUA_6G019404

0.965

DGUA_6G005246

0.963

DGUA_6G016811

0.940

DGUA_6G005294

0.939

DGUA_6G009613

0.931

DGUA_6G019939

0.931

Your Current Organism:

Drosophila guanche

NCBI taxonomy Id: 7266
Other names: D. guanche

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGUA_6G003919	DGUA_6G005246	A0A3B0KI80	A0A3B0JDA1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Blast:Fanconi anemia group M protein.	0.997
DGUA_6G003919	DGUA_6G005294	A0A3B0KI80	A0A3B0JI74	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Blast:Fragile X mental retardation syndrome-related protein 1.	0.427
DGUA_6G003919	DGUA_6G005916	A0A3B0KI80	A0A3B0JZL1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.985
DGUA_6G003919	DGUA_6G006507	A0A3B0KI80	A0A3B0J379	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Blast:Tudor domain-containing protein 3.	0.989
DGUA_6G003919	DGUA_6G008900	A0A3B0KI80	A0A3B0KND5	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.978
DGUA_6G003919	DGUA_6G009613	A0A3B0KI80	A0A3B0KN36	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Blast:ATP-dependent DNA helicase Q4.	0.969
DGUA_6G003919	DGUA_6G016811	A0A3B0KI80	A0A3B0KEY1	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.923
DGUA_6G003919	DGUA_6G019357	A0A3B0KI80	A0A3B0K8X5	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Blast:Crossover junction endonuclease MUS81.	0.988
DGUA_6G003919	DGUA_6G019404	A0A3B0KI80	A0A3B0K781	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Blast:DNA repair endonuclease XPF.	0.988
DGUA_6G003919	DGUA_6G019939	A0A3B0KI80	A0A3B0KT67	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Blast:Bloom syndrome protein homolog.	0.999
DGUA_6G005246	DGUA_6G003919	A0A3B0JDA1	A0A3B0KI80	Blast:Fanconi anemia group M protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.997
DGUA_6G005246	DGUA_6G005916	A0A3B0JDA1	A0A3B0JZL1	Blast:Fanconi anemia group M protein.	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.962
DGUA_6G005246	DGUA_6G006507	A0A3B0JDA1	A0A3B0J379	Blast:Fanconi anemia group M protein.	Blast:Tudor domain-containing protein 3.	0.963
DGUA_6G005246	DGUA_6G008900	A0A3B0JDA1	A0A3B0KND5	Blast:Fanconi anemia group M protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.992
DGUA_6G005246	DGUA_6G009613	A0A3B0JDA1	A0A3B0KN36	Blast:Fanconi anemia group M protein.	Blast:ATP-dependent DNA helicase Q4.	0.969
DGUA_6G005246	DGUA_6G016811	A0A3B0JDA1	A0A3B0KEY1	Blast:Fanconi anemia group M protein.	Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.	0.747
DGUA_6G005246	DGUA_6G019357	A0A3B0JDA1	A0A3B0K8X5	Blast:Fanconi anemia group M protein.	Blast:Crossover junction endonuclease MUS81.	0.989
DGUA_6G005246	DGUA_6G019404	A0A3B0JDA1	A0A3B0K781	Blast:Fanconi anemia group M protein.	Blast:DNA repair endonuclease XPF.	0.858
DGUA_6G005246	DGUA_6G019939	A0A3B0JDA1	A0A3B0KT67	Blast:Fanconi anemia group M protein.	Blast:Bloom syndrome protein homolog.	0.997
DGUA_6G005294	DGUA_6G003919	A0A3B0JI74	A0A3B0KI80	Blast:Fragile X mental retardation syndrome-related protein 1.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.427