DGUA_6G006517 protein (Drosophila guanche) - STRING interaction network

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DGUA_6G006517

tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (274 aa)

Predicted Functional Partners:

DGUA_6G006778

0.996

DGUA_6G000343

0.992

DGUA_6G001279

0.966

DGUA_6G014126

0.912

DGUA_6G003947

0.765

DGUA_6G007513

0.724

DGUA_6G016576

0.713

DGUA_6G010415

0.653

DGUA_6G008576

0.636

DGUA_6G001672

0.635

Your Current Organism:

Drosophila guanche

NCBI taxonomy Id: 7266
Other names: D. guanche

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DGUA_6G000343	DGUA_6G001279	A0A3B0J203	A0A3B0JM79	Sen15 domain-containing protein.	Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.	0.956
DGUA_6G000343	DGUA_6G001672	A0A3B0J203	A0A3B0J430	Sen15 domain-containing protein.	Blast:Ribonuclease Z, mitochondrial.	0.432
DGUA_6G000343	DGUA_6G003947	A0A3B0J203	A0A3B0KGL5	Sen15 domain-containing protein.	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.	0.425
DGUA_6G000343	DGUA_6G006517	A0A3B0J203	A0A3B0J386	Sen15 domain-containing protein.	tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]	0.992
DGUA_6G000343	DGUA_6G006778	A0A3B0J203	A0A3B0JU83	Sen15 domain-containing protein.	Blast:tRNA-splicing endonuclease subunit Sen54.	0.992
DGUA_6G000343	DGUA_6G014126	A0A3B0J203	A0A3B0K8C2	Sen15 domain-containing protein.	Blast:tRNA-splicing endonuclease subunit Sen2.	0.869
DGUA_6G001279	DGUA_6G000343	A0A3B0JM79	A0A3B0J203	Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.	Sen15 domain-containing protein.	0.956
DGUA_6G001279	DGUA_6G003947	A0A3B0JM79	A0A3B0KGL5	Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.	0.701
DGUA_6G001279	DGUA_6G006517	A0A3B0JM79	A0A3B0J386	Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.	tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]	0.966
DGUA_6G001279	DGUA_6G006778	A0A3B0JM79	A0A3B0JU83	Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.	Blast:tRNA-splicing endonuclease subunit Sen54.	0.983
DGUA_6G001672	DGUA_6G000343	A0A3B0J430	A0A3B0J203	Blast:Ribonuclease Z, mitochondrial.	Sen15 domain-containing protein.	0.432
DGUA_6G001672	DGUA_6G003947	A0A3B0J430	A0A3B0KGL5	Blast:Ribonuclease Z, mitochondrial.	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.	0.433
DGUA_6G001672	DGUA_6G006517	A0A3B0J430	A0A3B0J386	Blast:Ribonuclease Z, mitochondrial.	tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]	0.635
DGUA_6G001672	DGUA_6G006778	A0A3B0J430	A0A3B0JU83	Blast:Ribonuclease Z, mitochondrial.	Blast:tRNA-splicing endonuclease subunit Sen54.	0.432
DGUA_6G001672	DGUA_6G010415	A0A3B0J430	A0A3B0J730	Blast:Ribonuclease Z, mitochondrial.	Blast:tRNA 2'-phosphotransferase 1.	0.588
DGUA_6G003947	DGUA_6G000343	A0A3B0KGL5	A0A3B0J203	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.	Sen15 domain-containing protein.	0.425
DGUA_6G003947	DGUA_6G001279	A0A3B0KGL5	A0A3B0JM79	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.	Protein CLP1 homolog; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation; Belongs to the Clp1 family. Clp1 subfamily.	0.701
DGUA_6G003947	DGUA_6G001672	A0A3B0KGL5	A0A3B0J430	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.	Blast:Ribonuclease Z, mitochondrial.	0.433
DGUA_6G003947	DGUA_6G006517	A0A3B0KGL5	A0A3B0J386	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.	tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]	0.765
DGUA_6G003947	DGUA_6G006778	A0A3B0KGL5	A0A3B0JU83	RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.	Blast:tRNA-splicing endonuclease subunit Sen54.	0.464

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