Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G001317Blast:NAD kinase. (498 aa)    
Predicted Functional Partners:
DGUA_6G001311
Blast:NAD kinase.
    
  0.998
DGUA_6G002073
NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
     
 0.989
DGUA_6G010672
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.986
DGUA_6G005217
Nicotinamide-nucleotide adenylyltransferase.
  
 
 0.985
DGUA_6G009531
Blast:Sterile alpha and TIR motif-containing protein 1.
     
 0.978
DGUA_6G013859
Blast:NAD-dependent histone deacetylase Sir2.
  
 
 0.977
DGUA_6G020354
NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.
  
 
 0.977
DGUA_6G015871
Blast:NAD-dependent protein deacetylase Sirt7.
  
 
 0.967
DGUA_6G013396
Blast:NAD-dependent protein deacetylase Sirt6.
  
 
 0.966
DGUA_6G017317
NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily.
  
 
 0.930
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
Server load: medium (48%) [HD]