Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G006932Blast:DNA polymerase eta. (894 aa)    
Predicted Functional Partners:
DGUA_6G009917
DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.
   
 0.989
DGUA_6G001978
Blast:DNA polymerase zeta catalytic subunit.
   
 0.988
DGUA_6G020157
Blast:RING finger and CHY zinc finger domain-containing protein 1.
    
 0.977
DGUA_6G000762
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.973
DGUA_6G004504
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.973
DGUA_6G007529
Blast:Ubiquitin-conjugating enzyme E2 variant 1.
    
 
 0.959
DGUA_6G016961
Blast:Mitotic spindle assembly checkpoint protein MAD2B.
   
 0.947
DGUA_6G013333
Blast:Ubiquitin-40S ribosomal protein S27a.
    
  0.939
DGUA_6G010813
Blast:DNA repair protein complementing XP-A cells homolog.
   
 0.921
DGUA_6G005916
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.
  
 0.885
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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