Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DGUA_6G006741Blast:FH2 domain-containing protein 1. (1643 aa)    
Predicted Functional Partners:
DGUA_6G011731
Blast:Protein cappuccino.
    
 0.975
DGUA_6G006585
Blast:Formin-like protein CG32138.
    
 0.964
DGUA_6G012498
Blast:Protein diaphanous.
    
 0.930
DGUA_6G004703
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
    
 0.929
DGUA_6G001521
Blast:Ras-like GTP-binding protein Rho1.
    
 0.902
DGUA_6G003589
Blast:Actin-binding protein anillin.
   
 0.884
DGUA_6G008962
Blast:Cdc42 homolog.
    
 0.872
DGUA_6G009710
Blast:Rho-related BTB domain-containing protein 1.
    
 0.870
DGUA_6G000655
Blast:Cofilin/actin-depolymerizing factor homolog; Belongs to the actin-binding proteins ADF family.
    
 
 0.867
DGUA_6G005702
Blast:Wiskott-Aldrich syndrome protein homolog.
   
 
 0.852
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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