Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DGUA_6G006739Blast:Protein male-specific lethal-3. (517 aa)    
Predicted Functional Partners:
DGUA_6G012255
Blast:Protein male-specific lethal-1.
    
 0.999
DGUA_6G003713
Blast:Dosage compensation regulator.
    
 
 0.996
DGUA_6G011483
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.995
DGUA_6G014886
Non-specific serine/threonine protein kinase.
    
 
 0.989
DGUA_6G005229
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.977
DGUA_6G004821
Blast:Zinc finger protein 235.
    
 0.964
DGUA_6G017025
Blast:PHD finger protein 20-like protein 1.
   
 0.953
DGUA_6G001448
Blast:MRG/MORF4L-binding protein.
   
 0.951
DGUA_6G001371
Blast:DNA methyltransferase 1-associated protein 1.
    
 0.945
DGUA_6G020407
Blast:Transcription-associated protein 1; Belongs to the PI3/PI4-kinase family.
   
 0.940
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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