Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G001811Mevalonate kinase. (389 aa)    
Predicted Functional Partners:
DGUA_6G004502
Blast:Probable phosphomevalonate kinase.
   
 
 0.997
DGUA_6G017812
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 0.996
DGUA_6G008678
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
 
 
 0.995
DGUA_6G000913
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.924
DGUA_6G004086
Blast:Cystathionine gamma-lyase.
 
    
 0.901
DGUA_6G016060
Blast:Ras-related protein Rab-1A.
  
 
 0.885
DGUA_6G013191
Blast:Hydroxymethylglutaryl-CoA lyase, mitochondrial.
    
 0.879
DGUA_6G001568
Blast:Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 0.862
DGUA_6G010947
Blast:Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.801
DGUA_6G014575
Blast:Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.763
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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