Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DGUA_6G007299Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (307 aa)    
Predicted Functional Partners:
DGUA_6G007782
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.843
DGUA_6G002851
Blast:Methyltransferase-like protein 25.
      
 0.770
DGUA_6G019931
Blast:Myotubularin-related protein 13.
      
 0.683
DGUA_6G016942
Protein-L-isoaspartate O-methyltransferase.
    
 
 0.682
DGUA_6G000826
Blast:LETM1 and EF-hand domain-containing protein anon-60Da, mitochondrial.
      
 0.653
DGUA_6G013805
Blast:Ras-related and estrogen-regulated growth inhibitor.
      
 0.648
DGUA_6G014529
Blast:Probable deoxycytidylate deaminase.
      
 0.641
DGUA_6G010385
SAM-dependent MTase TRM10-type domain-containing protein.
   
  
 0.613
DGUA_6G007120
Blast:Methyltransferase-like protein 5.
   
  
 0.612
DGUA_6G017752
Blast:Activating signal cointegrator 1 complex subunit 3.
      
 0.592
Your Current Organism:
Drosophila guanche
NCBI taxonomy Id: 7266
Other names: D. guanche
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